Specificity of autoantibodies reacting optimally at 37°C
نویسندگان
چکیده
منابع مشابه
Autoantibodies reacting with heart muscle tissue in coronary heart disease.
By the use of the thrombocyte consumption test (T.C.T.) autoantibodies reacting with heart muscle tissue have been demonstrated in 63.3% of the cases of coronary heart disease accompanied by different grades of insufficiency of the blood supply to the heart muscle. These autoantibodies could be detected two to three weeks after the onset in most patients experiencing a coronary attack for the f...
متن کاملSpecificity of autoantibodies in autoimmune thrombocytopenia.
In 42 patients with autoimmune thrombocytopenia (AITP) and a positive direct platelet suspension immunofluorescence test (PSIFT), the antigenic specificity of the autoantibodies was studied. Because the autoantibodies were often not detectable in the serum and additional HLA antibodies may disturb the reaction pattern with the platelet panel, we used eluates prepared from the patients' platelet...
متن کاملSpecificity of autoantibodies to lactate dehydrogenase isoenzyme subunits.
We studied serum from 12 unrelated patients with variant electrophoretic patterns for lactate dehydrogenase (EC 1.1.1.27; LD) isoenzymes characteristic of LD-immunoglobulin complexes. Immunoglobulin class was identified in four cases. In all 12 cases, mixing the patient's serum with control serum altered the mobility of normal LD isoenzymes to that of the variant. To determine antigenic specifi...
متن کاملAutoantibodies with Mimicking Specificity Detected by the Dilution Technique in Patients with Warm Autoantibodies
BACKGROUND The aim of this study was to investigate the frequency of autoantibodies with mimicking specificity by using the dilution technique, to assess the usefulness of the combination of the dilution technique and red blood cell (RBC) phenotyping, and to establish a pre-transfusion testing algorithm in patients with warm autoantibodies. METHODS Serum samples from 71 patients with warm aut...
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Sera from 151 patients with a variety of cancers were screened for antibody-like activity against lipoproteins. Eighteen % of the sera exhibited activity against autologous and homologous high-density lipoproteins and 3% exhibited activity autologous and homologous low-density lipoprotiens. Antibody-like binding was proven by its restriction to the Fab fragment of IgG. The reactive part of the...
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ژورنال
عنوان ژورنال: Immunohematology
سال: 2020
ISSN: 0894-203X,1930-3955
DOI: 10.21307/immunohematology-2019-609